Epidural clonidine used as an adjunct to local anesthetics has 3 diverse mechanisms of action. Initial, the stimulation of alpha-2-receptors in the dorsal horn decreases suffering transmission. Next, clonidine may cause area vasoconstriction that restrictions vascular removal of local epidural anesthetics. May be supplied as monotherapy or as adjunctive https://bookmarksden.com/story19919778/the-2-minute-rule-for-onolidine